Sickle cell anaemia results from:

1. A chromosomal aberration
2. Non-disjunction of autosome
3. A point mutation
4. Blood transfusion reaction
Subtopic:  Mutation |
 94%
Level 1: 80%+
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Point mutation involves:

1. insertion
2. change in single base pair
3. duplication 
4. deletion
Subtopic:  Mutation |
 92%
Level 1: 80%+
AIPMT - 2009
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Which one of the following is a wrong statement regarding mutations?

1. Deletion and insertion of base pairs cause frame-shift mutations
2. Cancer cells commonly show chromosomal aberrations
3. UV and Gamma rays are mutagens
4. Change in a single base pair of DNA does not cause mutation
Subtopic:  Mutation |
 90%
Level 1: 80%+
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Identify the incorrect statement:

1. In addition to recombination, mutation is another phenomenon that leads to variation in DNA.
2. Chromosomal aberrations are commonly observed in cancer cells.
3. A classical example of a point mutation is sickle cell anemia.
4. Non ionising radiations cannot be mutagens.
Subtopic:  Mutation |
 83%
Level 1: 80%+
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A mutagen causes mutation by:
1. Changing amino acid sequence
2. Modifying DNA structure
3. Altering protein folding
4. Affecting RNA processing
Subtopic:  Mutation |
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