When the human genome was first sequenced, scientists expected to find around 100,000 genes (which corresponded to the estimated number of different proteins in a human). Upon its completion and analysis of reading frames, they discovered the number was more likely 25,000. What is the most likely explanation for this?

1. Gene editing
2. Alternative splicing
3. Exon shuffling
4. Intron excision

Subtopic:  Transcription: I | Transcription:II | Transcription: III | Transcription: IV | Human Genome Project |
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What percent of the human DNA actually codes for proteins?
1. Less than 2%
2. Around 20%
3. Between 35% and 40%
4. More than 98%
Subtopic:  Human Genome Project |
 94%
Level 1: 80%+
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Commonly used vectors for human genome sequencing are:

1. T-DNA 2. BAC and YAC
3. Expression Vectors 4. T/A cloning Vectors
Subtopic:  Human Genome Project |
 92%
Level 1: 80%+
AIPMT - 2014
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Which of the following was not a goal of the HGP?

1. To identify all the approximately 20,000-25,000 genes in human DNA.
2. To determine the sequences of the 3 billion chemical base pairs that make up human DNA.
3. To address the ethical, legal, and social issues that may arise from the project.
4. To clone a human being.
Subtopic:  Human Genome Project |
 91%
Level 1: 80%+
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Human Genome Project was launched in the year:

1. 1990 2. 2003
3. 2006 4. 2011
Subtopic:  Human Genome Project |
 89%
Level 1: 80%+
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Identify the incorrect statement.
1. The Human Genome Project revealed that the human genome contains 3164.7 million base pairs.
2. One of the unexpected findings of the Human Genome Project was the high amount of non-coding DNA in the human genome.
3. The Human Genome Project was completed within five years of its inception.
4. The Human Genome Project's findings are used to understand genetic predispositions to various diseases.
Subtopic:  Human Genome Project |
 89%
Level 1: 80%+
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The largest gene in a man is:

1. Insulin gene

2. Tumour suppressor gene

3. Beta globin gene of haemoglobin

4. Dystrophin

Subtopic:  Human Genome Project |
 89%
Level 1: 80%+
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What was the primary aim of the Human Genome Project (HGP)?
1. To map only the protein-coding genes in the human genome.
2. To identify all genes, determine DNA sequences, and address ethical issues.
3. To create new species through genetic manipulation.
4. To replace faulty human genes with engineered ones.
Subtopic:  Human Genome Project |
 89%
Level 1: 80%+
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The number of genes present on the human - ‘‘Y’’- chromosome, is

1. 321

2. 123

3. 312

4. 231

Subtopic:  Human Genome Project |
 88%
Level 1: 80%+
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In the history of biology, the human genome project led to the development of:
1. Biosystematics
2. Biotechnology
3. Biomonitoring
4. Bioinformatics

Subtopic:  Human Genome Project |
 87%
Level 1: 80%+
AIPMT - 2011
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