- 1(current)
Q. No.The genetic basis of hemophilia, so common within European royal families, was revealed by studies of
1. DNA sequences.
2. chromosomes in gametes.
3. family pedigrees.
4. prenatal gene products.
1. DNA sequences.
2. chromosomes in gametes.
3. family pedigrees.
4. prenatal gene products.
Subtopic: Mendelian Disorders: Hemophilia |
95%
Level 1: 80%+
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The family pedigree of Queen Victoria shows a number of haemophilic descendants as she was:
1. Affected by the disease
2. Carrier for the disease
3. Did not carry the allele for haemophilia
4. Was not a queen
Subtopic: Mendelian Disorders: Hemophilia |
92%
Level 1: 80%+
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Which of the following most appropriately describes haemophilia?
1. X-linked recessive gene disorder
2. Chromosomal disorder
3. Dominant gene disorder
4. Recessive gene disorder
Subtopic: Mendelian Disorders: Hemophilia |
91%
Level 1: 80%+
NEET - 2016
Hints
Match the following Mendelian disorders with their characteristics:
Choose the correct matching:
| Disorder | Characteristics | ||
| A. | Haemophilia | 1. | Autosomal recessive; deficiency of enzyme converting phenylalanine to tyrosine |
| B. | Phenylketonuria | 2. | X-linked recessive; defect in blood clotting protein |
| C. | Sickle-cell anaemia | 3. | Autosomal recessive; quantitative problem - too few globin chains synthesized |
| D. | Thalassemia | 4. | Autosomal recessive; qualitative problem - Glu→Val substitution in \(\beta\)-globin |
| 1. | A-2, B-1, C-4, D-3 | 2. | A-1, B-2, C-3, D-4 |
| 3. | A-3, B-4, C-1, D-2 | 4. | A-4, B-3, C-2, D-1 |
Subtopic: Mendelian Disorders: Sickle Cell Anemia | Mendelian Disorders | Mendelian Disorders: Hemophilia | Mendelian Disorders: Thalassemia |
91%
Level 1: 80%+
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Identify the correct statements:
| A: | The possibility of a female becoming a haemophilic is extremely rare. |
| B: | X-linked recessive trait shows transmission from carrier female to male progeny. |
| 1. | Only A is correct |
| 2. | Only B is correct |
| 3. | Both A and B are correct |
| 4. | Both A and B are incorrect |
Subtopic: Mendelian Disorders: Hemophilia |
90%
Level 1: 80%+
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Haemophilia is an inherited bleeding disorder in which the blood does not clot normally due to lack of blood clotting proteins. This rare disease is commonly observed in human males than in females because it is caused by
| 1. | Y-linked recessive allele |
| 2. | X-linked recessive allele |
| 3. | Autosomal recessive allele |
| 4. | X-linked dominant allele |
Subtopic: Mendelian Disorders: Hemophilia |
88%
Level 1: 80%+
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If a male child inherits haemophilia, the gene must have come from
1. father
2. mother
3. both parents
4. mutation only
1. father
2. mother
3. both parents
4. mutation only
Subtopic: Mendelian Disorders: Hemophilia |
85%
Level 1: 80%+
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| Assertion(A): | Normal father and carrier mother can transfer haemophilia to son. |
| Reason(R): | Gene of haemophilia is located on autosome |
| 1. | Both (A) and (R) are True and (R) is the correct explanation of (A) |
| 2. | Both (A) and (R) are True and (R) is not the correct explanation of (A) |
| 3. | (A) is True but (R) is False |
| 4. | Both (A) and (R) are False |
Subtopic: Mendelian Disorders: Hemophilia |
82%
Level 1: 80%+
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Which of the following is not a hereditary disease:
1. Haemophilia
2. Cretinism
3. Cystic fibrosis
4. Thalasasemia
Subtopic: Mendelian Disorders: Hemophilia | Mendelian Disorders: Thalassemia |
81%
Level 1: 80%+
AIPMT - 2005
Hints
- 1(current)
Q. No.
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